Activity of chaperones in the endometrium in the presence of HIV

The presence of human immunodeficiency virus (HIV) as a cause acquired remains medical and social problem despite the success antiretroviral therapy. Heat shock proteins (heat-shock - HSP) are family produced by cells in response to stressful conditions. aim study was determine activity heat endometrium HIV infection. Research groups were formed with 25 cases each group: group infection, combination infection alcoholism, control group. An immunohistochemical conducted monoclonal antibodies HSP70 HSP90. During study, it established that its chronic alcoholism leads development pathological processes (or endometrium) signs microcirculatory channel disturbances, sclerotic changes, tendency endometrial atrophy. At same time, there is reliable activation HSP90, which can be sign early non-plastic changes endometrium. recognized immune system further humoral cellular immunity reactions. level increases foci inflammation, they also involved pathogenetic mechanisms almost all diseases.The expression increased from ([1.18±0.12] up ([2.27±0.14] ([2.71±0.13] HSP90 ([0.73±0.09] ([2.13±0.13] ([2.70±0.13] (p<0.05). Keywords: response, transformation, heat-shock proteins.